Our new Very clear+ tissue clearing strategy is the sole approach that delipidates samples without any transform in morphology and with negligible influence on structural integrity.

Megatome is often a vibrating microtome designed to section a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, in addition to minimum tissue hurt and information reduction.

Antibodies might consider weeks to diffuse by means of just a few millimeters of tissue, by using a steep labeling gradient from floor to Main.

Megatome is designed for precision: the blade vibrates at an increased frequency and bigger amplitude array than other microtomes, and contains a exceptional deflection Regulate system.

SE employs a rotational electric area to disperse highly electromobile molecules (such as antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,

Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This enables mild penetration in the sample and assures the acquisition of large-resolution, in-focus graphic megatomi.com knowledge.

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eFLASH is usually a speedy tissue labeling technique that enables for uniform entire-organ staining in twenty rounds of labeling.

The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace throughout intact tissue volumes, even though its modular design lets you upgrade and personalize person parts.

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Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, shielding specimens for multiple rounds of processing.

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Our novel Defend tissue preservation strategy kinds intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.